Direct access to content

Innovation Chimie Carnot NORMANDIE_UNIVERSITE




Carlos Afonso, Professor in Analytical Chemistry is a specialist in mass spectrometry. He is co-director for the analysis department of the Carnot I2C and responsible for the mass spectrometry group of the analysis and modeling team within the COBRA laboratory. He is also co-director of the C2MC joint laboratory, which brings together analytical teams from the University of Rouen, the University of Pau and TOTAL Refining & Chemistry. His research activities focus on the analysis of complex mixtures ranging from petrochemicals to polymers, as well as in the fields of biology and environment, combining mass spectrometry with other separation methods such as chromatography and / or ion mobility spectrometry.


Dr Muriel Bardor’s European PhD thesis focused on the N-glycosylation of recombinant mAb produced in transgenic plants. After her graduation in 2001, she joined Prof Ajit Varki’s group at the Glycobiology Research and Training Center, University of California San Diego, USA where she demonstrated the uptake mechanism of the non-human sialic acid N-glycolylneuraminic acid into human and mammalian cells. At the end of 2003, she obtained an Associate Professor position at the University of Rouen, France working in a project aiming to introduce in planta the sialylation pathway to optimize the production of plant made-biopharmaceuticals. From 2010-2012, she spent 2 years in Singapore as the Head of the Bioprocessing Technology Institute Analytics group were she managed a team composed of 3 research scientists, 1 PhD student and 7 research officers. During that time, the group has developed analytical methodologies dedicated to mammalian glycans and glycoproteins’characterization. She is currently a full professor at the University of Rouen Normandy, France, working in the Glyco-MEV laboratory EA4358 and responsible of an innovative research project dedicated to algae-made biopharmaceuticals. Pr Bardor has published more than 50 peer reviewed papers, 20 chapters and others writings, 7 patents. She has developed a large network of national and international collaborations. She led several scientific projects and coordinated research collaborative agreements with public and private institutions. Recently, she has been appointed as a junior member 2014 of the “Institut Universitaire de France” (IUF) thus reflecting the excellence of the science that she is leading.

Jean-François BRIERE

Jean-François Brière (Chargé de recherche CNRS). He is currently working in the field of organic chemistry in the laboratory COBRA at the university of Rouen Normandy focusing on the construction of biorelevant chiral heterocycles. His research themes aim at developing sustainable catalytic synthetic methodologies especially employing organocatalysts. He is also regularly involved into collaborations with industrial partners. In this context, he is responsible of the synthesis departments of the C2I-Orga platform and the tremplin I2C – Innovation Chemistry Carnot.


Pascal Cosette is professor of Chemistry at the University of Rouen where he is manager of the PISSARO proteomics facility. His expertise consists in the purification, identification and quantification of proteins/peptides in different kinds of samples, particularly in tissues or biological fluids to highlight new biomarkers.

Co-Manager of the Analytical Department of I2C. His missions are to coordinate the analysis activity, to orient the projects toward the most appropriate analytical solutions and to ensure that the analytical department of I2C is maintained at the best operational level.


After having completed a PhD in Chemistry of Materials, I joined in 2011 a position of Research Engineer in the Crystal Genesis unit of the SMS laboratory. Our expertise is mainly dedicated to the crystallization of molecular organic compounds. My specific scientific skills extend from Phase Diagram determination to the control of the physicochemical properties of crystalline materials (chemical and structural purity, polymorphism, etc.). My instrumental skills mainly concern the thermal and calorimetric analytical tools applied to organic substances. Recently, my research area focused on the chiral discrimination at the solid state and its involvement on the amorphous state of organic compounds (co-supervisor of Mr Bienvenu Atawa PhD thesis, defense scheduled in 2018). In the tremplin Carnot I2C structure, I am operational manager of Formulation/Polymer department (Rouen part).

Géraldine GOUHIER

Professor Géraldine Gouhier is the leader of supported and supramolecular chemistry group based on the chemistry on ionic liquid and cyclic oligosaccharides called cyclodextrins. Her expertise is to functionalized these supramolecular entities to reach innovative smart molecular MRI contrast agents for biomedical applications.

Business Development Manager. Promote and support I2C industrial partnerships and develop external cooperation to enhance research and development exchanges


Michel Grisel studied chemistry, and more specifically macromolecular chemistry, at the University of Sciences and Techniques in Rouen (France). He carried out doctoral studies at the Polymer, Biopolymers, Membranes (PBM) CNRS laboratory in Rouen, in the field of physical gelation of polysaccharides. In 1998, he joined the laboratory of chemistry (URCOM) at the University of Le Havre, France. Firstly assistant professor until 2006, he then became full time professor and is now the URCOM laboratory manager. Among different fields of interest, mainly related to polysaccharides, he and his team are interested in studying and understanding the role and properties of ingredients and formulations in the cosmetic field. His domains of interest, mainly in the cosmetic field, cover chemical, physical and physical-chemical characterizations of ingredients and complex mixtures mainly related to cosmetic science.


Marie Hubert-Roux is a research engineer in mass spectrometry. Her research activities deal with the development of new analytical methods in mass spectrometry and ion mobility. The subjects concern the molecular analysis in petrochemistry as well as the structural studies of organic molecules and polymers.
She is operational manager of analysis department of the Carnot I2C. Her missions are to advise the industrials in their analytical requests and to help the researchers for the industrial partnership.

Alexandra Le Foll – Devaux (Research engineer – INSA Rouen). Technical manager of synthesis department of the C2I-OrgA platform of COBRA laboratory and operational manager of the I2C synthesis department. She manages and supervises collaborated researches with industrial partners in the field of organic synthesis and purification technics within the platform C2I-OrgA. She has developed a special expertise in the synthesis and functionalization of heterocycles, organocatalysis, glycochemistry and molecularly imprinted polymers.


Professor Loïc Le Pluart is the leader of a polymer materials group investigating the chemistry-process-structure-properties relationships in polymer materials and polymer based composites. His expertise relates to nanocomposites materials developement by the incorporation of fuctional nanofillers in polymer matrices and blends.

Head of Formulation/Polymer Department. Surpervise and coordonate activities and projects dealing with formulation and polymers. Act as coordinator for I2C regarding the “Rendez-Vous Carnot”.


Vincent Levacher (CNRS research director) is the leader of the Heterocycles team and deputy director of COBRA. He is co-author of 130 scientific publications and co-inventor of 9 patents. The research activities of this team cover several methodological aspects of heterocyclic chemistry ranging from the C-H functionalization of nitrogen-containing heterocycles and sugars to asymmetric organocatalysis. The team enjoys a recognized expertise in pharmacochemistry of heterocycles (design, synthesis and biological evaluation of kinases and cholinesterases inhibitors). The development of chemical delivery systems to transport neuroactive compounds into the central nervous system has led in 2012 to the creation of VFP-Therapies company. Strongly involved in industrial partnerships and valorization of research for many years, he took in 2016 the leadership of “Innovation


Cécile Perrio is developing radiochemistry for PET imaging including radiosynthesis and in vivo preclinical evaluation of new radiotracers for clinical biomedical applications. Her expertise mainly focuses on carbon-11 and fluorine-18 radiochemistry, and on the radiolabeling of small molecules (aryl/heteroaryl/aliphatic structures, amino-acids), peptides, proteins and “biologics”.

Co-referent for the pharmaceutical sector


Chemical engineer and PhD in materials chemistry, Céline PICARD is expert « interactions ingredients/products/skin »: characterizing and understanding interactions between ingredients (emollients, texturing agents, TiO2 nanoparticles, actives, surfactants…) in complex formulations (emulsions, dispersions, gels…) and with skin: stability, texture properties, sensory properties, safety. Head of the Master degree Aroma, Perfumes and Cosmetics (ARPAC) of Le Havre Normandy University, she’s working in strong relationship with industry.

Cosmetics segment referent, in charge of the scientific animation and surveillance. Develop the scientific relationships with cosmetic industries.


Florence Portet-Koltalo is associate professor of University of Rouen-Normandy. Her researches focus on Separation Sciences that is on the development of methodologies of sample preparation and of chromatographic separation/quantification at trace levels of mixtures of organic molecules. She is now more specialized in environmental pollution issues, contaminants being in complex matrices such as air, water, soils or sediment. She is also contributing with her expertise in projects on remediation technologies (electrokinetic remediation, bioremediation, phytoremediation).

Florence Portet-Koltalo is a sectoral lead for I2C Carnot. She acts as a coordinator to maintain a technological survey in the “Energy and Environment” sectors and to ensure the visibility of the researches in these scientific areas.

Christophe ROCHAIS

Christophe Rochais is a Professor or Organic Chemistry in the Faculty of Pharmacy of the University of Caen-Normandie. He is the head of the polypharmacology research theme within the CERMN. His research interests include medicinal chemistry program in the field of enzymatic inhibition and receptor modulation in order to develop pharmacological tools and bioactive compounds. In the recent years, he studied the development of pleiotropic agents of interest in the treatment of Alzheimer's disease, which notably led to the discovery of the preclinical candidate Donecopride. He is developing several collaborative programs in the field of neurosciences, oncology with academic and pharmaceutical industries.

Head of I2C synthesis department. Develop I2C industrial partnerships with pharmaceutical and chemical industries.


Project Manager of CNRT Matériaux, Maud Ropert got the task to develop research partnerships with industry in the field of Materials Chemistry at the regional, national and international levels. In charge of the set up and the monitoring of partnership projects, she makes the link between industrials, researchers and supervisory administrations.

Operational Manager of Formulation and Polymer Department. Her mission in I2C is to schedule and set up projects in her thematic, and made their administrative, financial and operational monitoring.

Esplanade de la Paix / CS 14032 / 14032 Caen Cedex 5